In vitro dosimetry of agglomerates.

نویسندگان

  • V Hirsch
  • C Kinnear
  • L Rodriguez-Lorenzo
  • C A Monnier
  • B Rothen-Rutishauser
  • S Balog
  • A Petri-Fink
چکیده

Agglomeration of nanoparticles in biological fluids is a pervasive phenomenon that leads to difficulty in the interpretation of results from in vitro exposure, primarily due to differing particokinetics of agglomerates to nanoparticles. Therefore, well-defined small agglomerates were designed that possessed different particokinetic profiles, and their cellular uptake was compared to a computational model of dosimetry. The approach used here paves the way for a better understanding of the impact of agglomeration on the nanoparticle-cell interaction.

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عنوان ژورنال:
  • Nanoscale

دوره 6 13  شماره 

صفحات  -

تاریخ انتشار 2014